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Anti -Fas Mouse mAb




货号:GB12089

规格:100 μl

交货周期:现货

运杂费: 登录后可查看运杂费

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产品属性


反应种属 H,M
来源宿主 Mouse
试验方法 IHC、IF
标记 无标记
类别 一抗

Product Information

 

Description

 

Fas mouse monoclonal

Protein full name

Tumor necrosis factor receptor superfamily member 6

Synonyms

FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, Fas cell surface death receptor

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse FAS
Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane,Secrete

Uniprot ID

P25445,P25446

 

 


 

Applications

 

Applications

IHC,IF

   
Species

Human,Mouse

   
Dilution

1:200-1:800

   
Positive tissue

Gallbadder,colon

   

 

 


 

Background

 

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

 

 

     


 

Images

 

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Immunohistochemistry analysis of paraffin-embedded human gallbladder  using FAS (GB12089) at dilution of 1:200

   

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Immunohistochemistry analysis of paraffin-embedded mouse colon  using FAS (GB12089) at dilution of 1:400

   
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Immunohistochemistry analysis of paraffin-embedded mouse testis using FAS (GB12089) at dilution of 1:400

 


 

 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

 

NOTE: This product is intended for research only.